In SCP: Secret Laboratory, players assume various roles within a randomly generated underground facility, where they must complete objectives while navigating the dangers posed by SCP entities. The game features a mix of survival and strategy mechanics, as players can choose to cooperate or compete against each other.

The storyline revolves around a containment breach at the SCP Foundation facility, where various anomalous entities escape their containment chambers, leading to chaos and danger. Players must either escape, neutralize threats, or fulfill their objectives based on their assigned roles.

SCP: Secret Laboratory stands out with its dynamic gameplay, where the random generation of the facility and role assignments ensure that each match is unique and unpredictable, enhancing the horror experience.