In Monster Rancher 4, players can breed and train multiple monsters simultaneously, utilizing a variety of training equipment and customizing their training facilities for optimal results. The game emphasizes strategic planning in training to improve monster performance in battles.

The storyline of Monster Rancher 4 revolves around the player's journey to become a top monster trainer, exploring various environments and engaging in battles while discovering new monsters. Players can unlock these monsters by inserting other CDs and DVDs into their console, adding a unique twist to the gameplay.

Monster Rancher 4 stands out with its innovative use of real-world media to generate in-game content, allowing for a diverse range of monsters and enhancing the overall experience of monster collection and training.