In Lost Dimension, players engage in a deep turn-based tactical combat system, where they can defer turns, assist allies, and combine psychic powers to achieve victory. The game emphasizes strategic planning and relationship-building among squad members, as players must identify hidden traitors within their ranks.

The storyline of Lost Dimension unfolds in a near-future world threatened by a terrorist known as 'The End.' Players control Sho Kasugai, a leader of a team of psychics, as they ascend a tower to confront this antagonist while uncovering the mysteries of their own pasts.

Lost Dimension stands out with its unique traitor mechanic, where players must use psychic abilities to delve into teammates' minds, revealing secrets and altering the gameplay experience with each playthrough. The game also features multiple endings, encouraging exploration and replayability.